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The effects of synthesizing human growth hormone (HGH) has long been a topic of discussion.

While there are many HGH synthetic products, accurately stimulating the naturally pituitary gland-produced hormone has been a trial and error experiment. That’s because HGH is tightly linked with the body’s endocrine system which impacts a person’s cell regeneration, growth, muscle, and bone development.

Homeopathic human growth hormone (HGH) gels (manufactured in FDA-approved facilities) are quickly becoming a revolutionary HGH supplement option in today’s pharmaceutical scene. We’re breaking down what you need to know about HGH gels while reviewing three popular HGH supplements.

What Is HGH Gel

Hearing of a product promising eternal youth with its driven anti-aging properties can raise cautious intrigue, as is the case of HGH gels. These homeopathic product dilations enrich the body with HGH-like benefits, and are absorbed through the skin (transdermal).

While growth hormone is associated with stimulating the body’s healing factor, increased stamina, muscle development, bone density, cell regeneration, tissue healing, and anti-aging, the extent of benefits the user gets through transdermal means is limited but not non-existent.

HGH gels are easier for wide demographic use and are better alternatives to HGH injections, especially if you’re afraid of needles. The active ingredient in most HGH gels is Somatropin, a synthetic USP human growth hormone used in treating a number of medical conditions among children, such as [1][2]:

  • Idiopathic Growth Hormone Deficiency.
  • Dwarfism.
  • Turner syndrome.
  • Prader-Willi syndrome.

All three groups showed positive results following their treatment with Somatotropin

The gel comprises HGH dilution levels ranging from 1x to 30x. In its dilated transdermal state, the drug effectively seeps into the skin’s pores stimulating the body’s natural healing factor.

Moreover, people with ineffective digestive tracts should not fret as their stomach condition doesn’t affect the efficiency of the gel.

Homeopathic HGH gel can incite a sense of youthfulness and vibrancy as it’s much more manageable to apply across affected regions such as the face, etc. for smooth and effective anti-aging benefits and skin nourishment.

What Does HGH Gel Do?

Human growth hormone (HGH) gel enhances the body’s ability to repair and maintain healthy tissue, cell, and organ condition. It also speeds up healing after sustaining muscle injury.

The main appeal of HGH gels is in their homeopathic ability to reduce symptoms of aging such as:

  • Crow’s feet
  • Facial wrinkles
  • Saggy/buggy skin
  • Fine lines
  • Decreased collagen production
  • Uneven skin tone
  • Pigmentation

HGH gel can also provide other wholesome physiological and physical perks like:

  • Improved mood
  • Better sleep quality
  • Increased sexual performance
  • Increased stamina
  • Enhanced libido
  • Better cognitive function and memory
  • Ease joint pain
  • Aid in weight loss
  • Improve immune system functionality
  • Menopause symptom relief
  • Promotes hair growth

Transdermal HGH gels achieve these effects by stimulating the metabolic system. Once absorbed in the skin, the gels compounds trigger the liver, producing insulin-like proteins and cartilage cells.

These cells play a vital role in the body’s protein synthesis responsible for bone development, muscle mass, and activating the body’s healing factor. Protein synthesis is useful in a number of areas like enhancing exercise and athletic performance or treating growth hormone deficiency in adults with HIV or AIDS [3].

Is HGH Gel FDA Approved?

Not quite. Somaderm is well-reviewed, but being homeopathic, it’s outside the FDA’s regulatory role. Seek advice from your doctor before using HGH gel, especially if you’re pregnant or lactating as somatropin could influence a child’s development and health [4].

Many new HGH gel products like Somaderm are available without a prescription at your local pharmacy. Despite their availability and affordable price, not all homeopathic products should be considered safe if not manufactured under FDA-approved conditions.

Moreover, because HGH gel products are available over the counter, off-label malpractice and excessive transdermal delivery risk are high which may negatively impact your health leading to overdosing symptoms such as:

  • Mood swings
  • Rashes
  • Nausea
  • Joint ache
  • Diarrhea
  • HGH gut
  • Hot flashes
  • Insomnia

It’s crucial to discard any miraculous gel claims you hear without carrying out your research. It is advisable to read the content and label information of any potential drug before use. Stick to their recommended doses as instructed on the label or by your doctor to avoid negative side effects.

Reviews of the Best HGH Gels and Non-Transdermal Alternatives

While there are several products in the market, like Tru Niagen and Nugenix HGH boost, high in somatropin ingredients, they fall short on transdermal use.

The good news is such products are readily available without a prescription. But if you’re looking for somatropin-rich homeopathic ingredients, at an affordable price, Somaderm gel might be your best bet.

To make things even easier, we have reviewed some of the best HGH gel options in today’s market and their extensive anti-aging benefits supporting a healthy lifestyle and wholesome appearance.

#1 GenF20 Plus

While there are many medical HGH supplements on the market today, not all trigger optimal growth hormone production. With GenF20 Plus, one can get adequate HGH stimulation in potent yet small doses.

It is an approved HGH emitter in tablet form produced from 100% organic ingredients. Despite its transdermal inability, it still proves a nonintrusive and safer alternative than the HGH injection form. Each bottle is naturally stripped off synthetic fillers and artificial compounds making it a versatile health drug with plant-based ingredients including:

  • Anterior pituitary powder
  • Deer velvet antler
  • Colostrum
  • Astragalus root extract (milkvetch)

Astragalus extract mixture showed to increase the tibial length of subjects over a two-week study

GenF20 Plus is mainly a unisex supplement (read more on HGH for Women products in our other article) enclosed in an enteric absorbent coating allowing the body to steadily absorb the drug’s natural ingredient base without waste.

Its special casing also helps prevent drug content from prematurely dissolving in your stomach acid. Without the coating, users would only get 10% of the drug’s full potential, opposed to an 80% potency boost.

The price of buying a special coating drug can be expensive. On the bright side, you can easily get it without a prescription from all leading pharmacies.

The drug also helps stimulate better skin glow and boosts metabolic system activity for better and efficient digestion. Consult your physician before switching to GenF20 plus as you might be required to change your diet to prevent drug (or substance) interactions.

#2 Somaderm

Somederm gel is a transdermal homeopathic product featuring somatropin as its main ingredient and adrenal/thyroid support.

For a reasonable price, you can experience Somaderm’s natural potent botanical herbs including:

  • Green tea
  • Licorice root
  • Aloe vera
  • Wild yam root
  • Ginkgo biloba
  • Epimedium
  • Velvet bean seed
  • Chaste tree fruit

Despite the backlash against New U Life miracle healing claims, a study proves the product’s ability to skyrocket HGH levels briefly by up to 878% in a study conducted on 15 male participants [5].

Somaderm gel is a natural supplement that doesn’t contain HGH, making it a safe product you can rely on based on authoritative certification. It also contains the highest possible dose of homeopathic HGH compared to other products in the market today making it a great option for treating GH deficiency in toddlers and adults.

However, one should always take caution and monitor their dosage effectively. Speak to your doctor or read the official label for more drug information and dosage requirements before committing to Somaderm.

#3 Serovital HGH

Serovital HGH is a popular  dietary supplement manufactured in FDA-approved facilities. As people age, their overall HGH level begins to drop drastically resulting in symptoms including:

  • Fatigue/insomnia
  • Weight gain
  • Facial wrinkles
  • Low libido/sex drive
  • Mental fog

Unlike homeopathic Somaderm gel, this product isn’t transdermal, instead, it is ingested as a pill. Despite its mildly steep price, taking Serovital each day improves daily function and increases HGH level due to essential amino acid content supporting optimal IGF-1 growth factor production.

Serovital claims to trigger leaner muscle mass and weight loss, especially when coupled with exercise or moderate activity. While the role of amino acids in protein synthesis and growth hormone increase could play a vital role in this, there is no reliable information to support these claims.

Adults are advised to consume 4 tablets each day. You may choose to take two in the morning and evening in between day-to-day meals. You also should avoid eating for at least two hours after taking Serovital and refrain from exceeding the recommended dose.

If unsure, check the label for more information or consult your doctor before integrating Serovital into your diet.

Is HGH Gel Effective?

Yes, HGH gel is an effective growth hormone treatment option and is relatively easy to obtain legally. Unlike GH injections, gels are non-intrusive and don’t leave irritable pain on injection sites.

Their smooth texture makes it easy to apply across the body making it effective for anti-aging and cosmetic purposes. What makes most HGH gel products effective is their homeopathic and transdermal nature. Both elements help make the gel easier to use and apply, supporting quick absorption compared to drugs.

Moreover, gels are cheaper, costing a couple of hundred bucks whereas the price of GH injection tops over a grand. They also incur less severe reactions, as nearly 30% of people suffer from GH injection side effects such as [6]:

  • Fluid retention
  • Carpal tunnel syndrome
  • Joint pain
  • Increased blood sugar
  • Muscle aches
  • Numbness
  • Nerve pain

GH deficient adults might develop more muscle mass, energy, stamina, and overall exercise capacity using growth hormone supplements and HGH gel. While the full scope of synthetic hormone efficacy is inconclusive, research by the National Institute on Aging (NIA) suggests its potential in promoting longevity [7].

Where Do You Apply HGH Gel?

Because HGH gels are transdermal, people are encouraged to apply them on thin and exposed skin areas such as forearms, armpits, or underarms.

Depending on your desired treatment, one may also apply the gel on their forehead and face which helps combat symptoms like wrinkles and fine lines, or spread it behind the knees and wrists for maximum absorption.

Consider applying the gel as needed day-by-day for effective results especially when treating medical conditions like mild arthritis or short bowel syndrome.


Before opting for a transdermal HGH treatment, you might have a few more unanswered questions. We’re answering some of the most commonly-asked questions by the public.

What Are the Side Effects of HGH Gel?

The side effects of growth hormone transdermal gel are similar to other HGH treatments. Common effects include, but are not limited to, carpal tunnel syndrome, muscle and joint pain, and swelling in arms or legs.

Does HGH Reduce Weight?

HGH treatments can help one to lose a few extra pounds, however, using human growth hormone for the purpose of weight loss is rather controversial and experimental.

Growth hormone therapy showed to reduce BMI SDS in obese boys

When combined with regular exercise and diet, you should be able to shed some weight. Although transdermal gel won’t have much of an impact on your weight loss goals, whereas injections have shown to decrease fat storage while increasing muscle mass to some extent [8].

What Happens When You Stop Taking HGH?

Both physical and psychological effects can occur after stopping HGH treatment, such as decreased energy, tiredness, depression, irritability, pain, and an increase in fat mass.

Although the mentioned symptoms can occur, you can still maintain the benefits of human growth hormone by adjusting your lifestyle.

Small changes, such as getting enough sleep, regular exercise, and reducing stress can help to keep your HGH levels optimal.

Does HGH Increase Weight?

No, HGH should not increase your weight. A common symptom of GHD in adults is weight gain, or more specifically, increased fat accumulation. With HGH treatments, fat mass is reduced, leaving you with lean body mass.


Growth hormone serves a vital role in the development of healthy bones, muscles, and immune systems throughout childhood. As people age, the need for essential HGH is intensified.

You can halt any diverse change experienced as a result of old age by maintaining your growth hormone levels and preventing GH deficiency. Pills and gels supplements like Somaderm provide essential growth hormones and free radicals which help deviate oxidative stress—a key factor in rapid aging caused by UV irritation.

By choosing an appropriate transdermal gel or drug, you can repair oxidation damage inflicted on protein molecules and cells by stimulating natural protein synthesis. This process helps regenerate damaged cells, tissue, and muscle fiber ultimately restoring your health and appearance.

Consider encouraging a lifestyle of frequent exercise and good nutrition to boost any supplement efficacy use while keeping you active, toned, and stronger.


  1. “Drug Information Portal – Mobile – U.S. National Library of Medicine – Drug Search Results.” U.S. National Library of Medicine, National Institutes of Health,
  2. Center for Drug Evaluation and Research. “Somatropin Information.” U.S. Food and Drug Administration, FDA,
  3. “Somatropin – Health Professional: NIH.” Somatropin – Health Professional | NIH,
  4. A;, Vila G;Luger. “Growth Hormone Deficiency and Pregnancy: Any Role for Substitution?” Minerva Endocrinologica, U.S. National Library of Medicine,
  5. Rick J. Alleman, Robert E. Canale. “A Blend of Chlorophytum Borivilianum and Velvet Bean Increases Serum Growth Hormone in Exercise-Trained Men – Rick J. Alleman, Robert E. Canale, Cameron G. McCarthy, Richard J. Bloomer, 2011.” SAGE Journals,
  6. Publishing, Harvard Health. “Growth Hormone, Athletic Performance, and Aging.” Harvard Health,

Kim, Nam, Song, Lim, Lee, Huh “Low-dose growth hormone treatment with diet restriction accelerates body fat loss.” Division of Endocrinology, 1999.

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